Secret of Mana! I'll forever love this game, it's so good and so much fun and I just can't wait for the remake.
Honorable mentions include Yoshi's Island, Zelda: ALTTP and Donkey Kong Country. There's some others I liked playing but mostly really rarely (like F-Zero).
Chrono Trigger or LoZ:ALTTP. Chrono Trigger has awesome artwork, and I love the team attacks and story. Plus, Chrono Trigger is a timeless classic. LoZ:ALTTP was probably my first LoZ game and one of my first SNES game. I sunk a lot of hours into it, and it really got me hooked into the series as a whole.